1+ week, 5+ day ago   (1065+ words) Ultragenyx's FDA-approved gene therapy for glycogen storage disease type Ia (GSD1a), Genglycos, may prevent deadly hypoglycemia for patients with specific genotypes By Jonathan D. Grinstein, PhD The consequence has been a never-ending spell of anxiety and exhaustion. “We’ve never slept through the…...

2+ week, 4+ day ago   (453+ words) Low-carb diets radically alter the balance of microbes in the gut with changes depending on whether fats or proteins are used as substitutes, preclinical research suggests. The canine study, reported in PNAS, suggests that low-carbohydrate (LC) diets extensively reprogram the gut,…...

2+ week, 4+ day ago   (419+ words) Researchers from the University of Exeter in the U.K. have shown that incorporating a type 1 diabetes genetic risk score (T1DGRS) into standard testing for maturity-onset diabetes of the young (MODY) could identify hidden type 1 diabetes in around one in six patients with…...

3+ week, 2+ day ago   (252+ words) An oral small molecule that increases energy expenditure rather than suppressing appetite produced substantial weight loss while preserving lean mass in mouse models of obesity, suggesting a potentially complementary strategy to GLP-1–based therapies. In mice with high-fat diet-induced obesity,…...

3+ week, 5+ day ago   (215+ words) Researchers in Sweden have discovered that, with the right diet, gut bacteria can produce molecules that reduce the risk of cardiovascular and metabolic diseases. In a study published in Cell, the team uncovered a previously unknown link between diet, the…...